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우정바이오-파스퇴르硏, 신약후보물질 발굴 공동연구 - 바이오스펙테이터

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우정바이오-파스퇴르硏, 신약후보물질 발굴 공동연구

입력 2019-03-13 10:44 수정 2019-03-13 10:44

바이오스펙테이터 장종원 기자

업무협약 체결..간암동물모델 구축 및 항암효능평가 과제 공동진행

▲우정바이오 최우성 전략기획이사(앞줄 왼쪽부터) 천병년 대표이사, IPK의 류왕식 소장, 스펜서쇼트 부소장 서행란 종양생물학팀장이 우정바이오연구팀과 함께 사진촬영을 하고 있다. 우정바이오 제공.

한국파스퇴르연구소와 우정바이오가 신약개발을 위한 공동연구를 진행한다. 한국파스퇴르연구소의 신약개발 플랫폼과 우정바이오의 개발프로세스를 접목해 효율적인 신약후보물질 발굴이 목적이다.

우정바이오는 최근 한국파스퇴르연구소와 신약개발을 위한 공동 연구 업무협약을 체결하고 감염병 연구와 치료제개발에 나서기로 했다고 13일 밝혔다.

이번 협약은 한국파스퇴르연구소가 구축하는 감염병 연구데이터를 활용한 세포기반의 신약개발 플랫폼을 우정바이오 신약클러스터의 개발프로세스와 접목시켜 효율적인 신약후보물질 발굴에 목적이 있다.

천병년 우정바이오 대표는 "MERS, SARS 및 슈퍼박테리아 발생현장 처리경험과 다양한 질환동물모델을 갖고 있는 우정바이오와 파스퇴르 연구소의 협력은 감염병 예방에서 치료제 개발까지 염두에 둔 포석"이라고 설명했다.

우정바이오는 뎅기열, 지카 바이러스 등 대응 연구개발에 활용되는 AG129 마우스를 제공하는 등 이미 다양한 질병 동물모델을 보유하고 있다.

양 기관은 협력의 일환으로 올해 4월부터 간암동물모델 구축 및 항암효능평가 과제를 공동 진행할 예정이다. 우정바이오는 암 환자에게서 유래한 암세포주를 이식한 동물모델 및 인간면역 이식 동물모델 등 첨단동물모델을 투입하여 항암신약 후보물질의 유효성을 평가할 예정이다.

환자유래이종이식(PDX) 동물모델을 이용한 시험법은 임상에서 성공 확률을 높일 수 있어 신약개발비용과 기간을 줄이는 효율적인 약물 효능평가 방법으로 주목 받아왔다.

한편 한국파스퇴르연구소(IPK)는 2004년 프랑스의 파스퇴르연구소와 한국과학기술연구원(KIST)이 과학기술정보통신부(MIST)의 지원을 받아 설립한 비영리 생명과학 연구기관이다.

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